Splice | Rotten Tomatoes (2025)

75% Tomatometer 199 Reviews 37% Popcornmeter 250,000+ Ratings

Geneticists Clive (Adrien Brody) and Elsa (Sarah Polley) specialize in creating hybrids of species. When they propose the use of human DNA, their pharmaceutical company bosses forbid it, forcing them to conduct experiments in secret. The result is Dren, a creature with amazing intelligence and physical attributes. At first, Dren exceeds their wildest dreams, but as she begins to grow at an accelerated rate, she threatens to become their worst nightmare.

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Splice

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Critics Consensus

It doesn't take its terrific premise quite as far as it should, but Splice is a smart, well-acted treat for horror fans.

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Critics Reviews

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Splice | Rotten Tomatoes (1) Hank Sartin Time Out Rated: 2/5 Nov 17, 2011 Full Review Splice | Rotten Tomatoes (2) Perri Nemiroff Shockya.com Fascinating and exciting yet disturbing and potentially upsetting. Rated: 4/5 Aug 13, 2010 Full Review Splice | Rotten Tomatoes (3) David Stratton At the Movies (Australia) I love the character of Dren, which is nerd spelt backwards. I loved the relationship between her and her putative parents: Adrian Brody and Sarah Polley. Rated: 3.5/5 Aug 11, 2010 Full Review Splice | Rotten Tomatoes (4) Patrick Cavanaugh The Wolfman Cometh Gets points for being bizarre and incorporating evocative body-horror elements, though the story itself doesn't offer up anything substantial. Rated: 2/5 Sep 22, 2023 Full Review Splice | Rotten Tomatoes (5) Brian Eggert Deep Focus Review In concept alone, not to mention the first exciting half-hour, the film promises greatness before failing to live up to those promises with a second half that feels emotionally disengaged and a finale that’s rushed. Rated: 2.5/4 Aug 18, 2023 Full Review Splice | Rotten Tomatoes (6) Rene Jordan El Nuevo Herald (Miami) Splice invents new nightmares with Dren. [Full review in Spanish] Jul 19, 2022 Full Review Read all reviews

Audience Reviews

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James N It’s a phobe but it’s like it was made for Amin. There’s clone sex that is almost a fucked her to death situation with incest undertones. Rated 1.5/5 Stars • Rated 1.5 out of 5 stars 10/29/24 Full Review Waniya S Kinky as hell anyways Rated 3/5 Stars • Rated 3 out of 5 stars 10/14/24 Full Review stephen b It's pretty disturbing, but in a way that forces you to think about the ethics of certain practices that may not be too far from reality. And then it just becomes really disturbing. Rated 3.5/5 Stars • Rated 3.5 out of 5 stars 09/21/24 Full Review David P I was pleasantly surprised. Weird, messed up but well worth a watch. Rated 3/5 Stars • Rated 3 out of 5 stars 08/18/24 Full Review Jordan Y Super weird and different. Rated 4/5 Stars • Rated 4 out of 5 stars 07/07/24 Full Review Joe W Once hallmark of poor writing is when any character can speak any line. In Splice the husband and wife team take turns being concerned, ambitious, loving their creation. Rated 2/5 Stars • Rated 2 out of 5 stars 07/04/24 Full Review Read all reviews

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Cast & Crew

Vincenzo Natali Director Adrien Brody Clive Sarah Polley Elsa Delphine Chaneac Dren Simona Maicanescu Joan Chorot David Hewlett Barlow
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Synopsis Geneticists Clive (Adrien Brody) and Elsa (Sarah Polley) specialize in creating hybrids of species. When they propose the use of human DNA, their pharmaceutical company bosses forbid it, forcing them to conduct experiments in secret. The result is Dren, a creature with amazing intelligence and physical attributes. At first, Dren exceeds their wildest dreams, but as she begins to grow at an accelerated rate, she threatens to become their worst nightmare.

Director
Vincenzo Natali

Producer
Steven Hoban

Screenwriter
Vincenzo Natali, Antoinette Terry Bryant, Doug Taylor

Distributor
Warner Bros. Pictures

Production Co
Gaumont

Rating
R (Language|Disturbing Elements|Nudity|Sci-Fi Violence|Strong Sexuality)

Genre
Sci-Fi, Horror

Original Language
English

Release Date (Theaters)
Jun 4, 2010, Wide

Release Date (Streaming)
May 19, 2016

Box Office (Gross USA)
$17.0M

Runtime
1h 47m

Sound Mix
Dolby Digital
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